Charismatic physicist, Jared Borowitz, is fast losing his sense of humour. Everywhere he looks he sees ignorant and superstitious fools. His mentor, a giant of science and logic, is dying. His ex-wife has switched gender preference. Entanglement ranges broadly across the tensions between science and belief, free will and fate, violence and justice, sex and love. The novel follows the transformation of a man of certainty and science when confronted with a world he does not know.